Kufareva, Irina: search on Z-Library

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1

What Do Structures Tell Us About Chemokine Receptor Function and Antagonism?

Kufareva, Irina, Gustavsson, Martin, Zheng, Yi, Stephens, Bryan S., Handel, Tracy M.

Journal:

Annual Review of Biophysics

Year:

2017

Language:

english

File:

PDF, 4.03 MB

english, 2017

2

Molecular mechanism of serotonin transporter inhibition elucidated by a new flexible docking protocol

Mari Gabrielsen, Rafał Kurczab, Aina W. Ravna, Irina Kufareva, Ruben Abagyan, Zdzisław Chilmonczyk, Andrzej J. Bojarski, Ingebrigt Sylte

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 2.04 MB

english, 2012

3

Identifying ligands at orphan GPCRs: current status using structure-based approaches

Ngo, Tony, Kufareva, Irina, Coleman, James L. J., Graham, Robert M., Abagyan, Ruben, Smith, Nicola J.

Journal:

British Journal of Pharmacology

Year:

2016

Language:

english

File:

PDF, 2.06 MB

english, 2016

4

PIER: Protein interface recognition for structural proteomics

Irina Kufareva, Levon Budagyan, Eugene Raush, Maxim Totrov, Ruben Abagyan

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2007

Language:

english

File:

PDF, 880 KB

english, 2007

5

Stoichiometry and geometry of the CXC chemokine receptor 4 complex with CXC ligand 12: Molecular modeling and experimental validation

Kufareva, Irina, Stephens, Bryan S., Holden, Lauren G., Qin, Ling, Zhao, Chunxia, Kawamura, Tetsuya, Abagyan, Ruben, Handel, Tracy M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 2.08 MB

english, 2014

6

Structure based prediction of subtype-selectivity for adenosine receptor antagonists

Vsevolod Katritch, Irina Kufareva, Ruben Abagyan

Journal:

Neuropharmacology

Year:

2011

Language:

english

File:

PDF, 2.55 MB

english, 2011

7

A General Method for Site Specific Fluorescent Labeling of Recombinant Chemokines

Kawamura, Tetsuya, Stephens, Bryan, Qin, Ling, Yin, Xin, Dores, Michael R., Smith, Thomas H., Grimsey, Neil, Abagyan, Ruben, Trejo, JoAnn, Kufareva, Irina, Fuster, Mark M., Salanga, Catherina L., Hand

Journal:

Year:

2014

Language:

english

File:

PDF, 5.40 MB

english, 2014

8

Negative allosteric modulators of the human calcium‐sensing receptor bind to overlapping and distinct sites within the 7 transmembrane domain

Josephs, Tracy M., Keller, Andrew N., Khajehali, Elham, DeBono, Aaron, Langmead, Christopher J., Conigrave, Arthur D., Capuano, Ben, Kufareva, Irina, Gregory, Karen J., Leach, Katie

Journal:

British Journal of Pharmacology

Year:

2019

File:

PDF, 1.69 MB

2019

9

[Methods in Enzymology] Chemokines Volume 570 || Disulfide Trapping for Modeling and Structure Determination of Receptor

Kufareva, Irina

Year:

2016

Language:

english

File:

PDF, 5.22 MB

english, 2016

10

Viral Infection Controlled by a Calcium-Dependent Lipid-Binding Module in ALIX

Bissig, Christin, Lenoir, Marc, Velluz, Marie-Claire, Kufareva, Irina, Abagyan, Ruben, Overduin, Michael, Gruenberg, Jean

Journal:

Developmental Cell

Year:

2013

Language:

english

File:

PDF, 2.00 MB

english, 2013

11

Quantum mechanics approaches to drug research in the era of structural chemogenomics

Ilatovskiy, Andrey V., Abagyan, Ruben, Kufareva, Irina

Journal:

International Journal of Quantum Chemistry

Year:

2013

Language:

english

File:

PDF, 338 KB

english, 2013

12

Receptor tyrosine kinases activate heterotrimeric G proteins via phosphorylation within the interdomain cleft of GÎ±i

Kalogriopoulos, Nicholas A., Lopez-Sanchez, Inmaculada, Lin, Changsheng, Ngo, Tony, Midde, Krishna K., Roy, Suchismita, Aznar, Nicolas, Murray, Fiona, Garcia-Marcos, Mikel, Kufareva, Irina, Ghassemian

Journal:

Proceedings of the National Academy of Sciences

Year:

2020

File:

PDF, 2.77 MB

2020

13

The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer

O'Hayre, Morgan, Vázquez-Prado, José, Kufareva, Irina, Stawiski, Eric W., Handel, Tracy M., Seshagiri, Somasekar, Gutkind, J. Silvio

Journal:

Nature Reviews Cancer

Year:

2013

Language:

english

File:

PDF, 3.05 MB

english, 2013

14

Pivotal role of P450–P450 interactions in CYP3A4 allostery: the case of α-naphthoflavone

Davydov, Dmitri R., Davydova, Nadezhda Y., Sineva, Elena V., Kufareva, Irina, Halpert, James R.

Journal:

Biochemical Journal

Year:

2013

Language:

english

File:

PDF, 785 KB

english, 2013

15

Novel cGMP Efflux Inhibitors Identified by Virtual Ligand Screening (VLS) and Confirmed by Experimental Studies

Sager, Georg, Ørvoll, Elin Ø., Lysaa, Roy A., Kufareva, Irina, Abagyan, Ruben, Ravna, Aina W.

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 4.48 MB

english, 2012

16

Optimization of High Throughput Virtual Screening by Combining Shape-Matching and Docking Methods

Lee, Hui Sun, Choi, Jiwon, Kufareva, Irina, Abagyan, Ruben, Filikov, Anton, Yang, Young, Yoon, Sukjoon

Journal:

Journal of Chemical Information and Modeling

Year:

2008

Language:

english

File:

PDF, 301 KB

english, 2008

17

Synthesis, Antidepressant Evaluation and Docking Studies of Long-Chain Alkylnitroquipazines as Serotonin Transporter Inhibitors

Gabrielsen, Mari, Wołosewicz, Karol, Zawadzka, Anna, Kossakowski, Jerzy, Nowak, Gabriel, Wolak, Małgorzata, Stachowicz, Katarzyna, Siwek, Agata, Ravna, Aina W., Kufareva, Irina, Kozerski, Lech, Bednar

Journal:

Chemical Biology & Drug Design

Year:

2013

Language:

english

File:

PDF, 962 KB

english, 2013

18

Structure-Based Predictions of Activity Cliffs

Husby, Jarmila, Bottegoni, Giovanni, Kufareva, Irina, Abagyan, Ruben, Cavalli, Andrea

Journal:

Journal of Chemical Information and Modeling

Year:

2015

Language:

english

File:

PDF, 1.73 MB

english, 2015

19

Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple

Aznar, Nicolas, Ear, Jason, Dunkel, Ying, Sun, Nina, Satterfield, Kendall, He, Fang, Kalogriopoulos, Nicholas A., Lopez-Sanchez, Inmaculada, Ghassemian, Majid, Sahoo, Debashis, Kufareva, Irina, Ghosh,

Journal:

Science Signaling

Year:

2018

Language:

english

File:

PDF, 7.05 MB

english, 2018

20

Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors

Kufareva, Irina, Bestgen, Benoit, Brear, Paul, Prudent, Renaud, Laudet, Béatrice, Moucadel, Virginie, Ettaoussi, Mohamed, Sautel, Celine F., Krimm, Isabelle, Engel, Matthias, Filhol, Odile, Borgne, Ma

Journal:

Scientific Reports

Year:

2019

File:

PDF, 2.22 MB

2019

21

Compound Activity Prediction Using Models of Binding Pockets or Ligand Properties in 3D

Kufareva, Irina, Chen, Yu-Chen, V. Ilatovskiy, Andrey, Abagyan, Ruben

Journal:

Current Topics in Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 487 KB

english, 2012

22

Dual Targeting of the Chemokine Receptors CXCR4 and ACKR3 with Novel Engineered Chemokines

Hanes, Melinda S., Salanga, Catherina L., Chowdry, Arnab B., Comerford, Iain, McColl, Shaun R., Kufareva, Irina, Handel, Tracy M.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 2.56 MB

english, 2015

23

Dynamic Structural Modeling Revealed That Nilotinib Inhibits Smoothened Signaling

Chahal, Kirti Kandhwal, Li, Jie, Kufareva, Irina, Durden, Donald, Reya, Robert Wechsler, Abagyan, Ruben, Chen, Clark C

Journal:

Year:

2019

Language:

english

File:

PDF, 91 KB

english, 2019

24

Discovery of novel membrane binding structures and functions 1

Kufareva, Irina, Lenoir, Marc, Dancea, Felician, Sridhar, Pooja, Raush, Eugene, Bissig, Christin, Gruenberg, Jean, Abagyan, Ruben, Overduin, Michael

Journal:

Biochemistry and Cell Biology

Year:

2014

File:

PDF, 2.68 MB

2014

25

Dual action calcium sensing receptor modulator unmasks novel mode-switching mechanism

Gregory, Karen J., Kufareva, Irina, Keller, Andrew Nathan, Khajehali, Elham, Mun, Hee-Chang, Goolam, Mahvash A, Mason, Rebecca S, Capuano, Ben, Conigrave, Arthur D., Christopoulos, Arthur, Leach, Kati

Journal:

ACS Pharmacology & Translational Science

Year:

2018

Language:

english

File:

PDF, 1.49 MB

english, 2018

26

CCR2-Mediated Uptake of Constitutively Produced CCL2: A Mechanism for Regulating Chemokine Levels in the Blood

Zhao, Bin N., Campbell, James J., Salanga, Catherina L., Ertl, Linda S., Wang, Yu, Yau, Simon, Dang, Ton, Zeng, Yibin, McMahon, Jeffrey P., Krasinski, Antoni, Zhang, Penglie, Kufareva, Irina, Handel,

Journal:

The Journal of Immunology

Year:

2019

File:

PDF, 1.86 MB

2019

27

Crosslinking-guided geometry of a complete CXC receptor-chemokine complex and the basis of chemokine subfamily selectivity

Ngo, Tony, Stephens, Bryan S., Gustavsson, Martin, Holden, Lauren G., Abagyan, Ruben, Handel, Tracy M., Kufareva, Irina, Bertrand, Mathieu JM

Journal:

Year:

2020

File:

PDF, 8.68 MB

2020

28

Advances in GPCR Modeling Evaluated by the GPCR Dock 2013 Assessment: Meeting New Challenges

Kufareva, Irina, Katritch, Vsevolod, Stevens, Raymond C., Abagyan, Ruben

Journal:

Year:

2014

Language:

english

File:

PDF, 6.40 MB

english, 2014

29

The GAPs, GEFs, GDIs and…now, GEMs: New kids on the heterotrimeric G protein signaling block

Ghosh, Pradipta, Rangamani, Padmini, Kufareva, Irina

Journal:

Year:

2017

Language:

english

File:

PDF, 1.28 MB

english, 2017

30

Identification of Global and Ligand-Specific Calcium Sensing Receptor Activation Mechanisms

Keller, Andrew N., Kufareva, Irina, Josephs, Tracy M., Diao, Jiayin, Mai, Vyvyan T., Conigrave, Arthur D., Christopoulos, Arthur, Gregory, Karen J., Leach, Katie

Journal:

Molecular Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.40 MB

english, 2018

31

Synthesis, in vitro binding studies and docking of long-chain arylpiperazine nitroquipazine analogues, as potential serotonin transporter inhibitors

Małgorzata Jarończyk, Karol Wołosewicz, Mari Gabrielsen, Gabriel Nowak, Irina Kufareva, Aleksander P. Mazurek, Aina W. Ravna, Ruben Abagyan, Andrzej J. Bojarski, Ingebrigt Sylte, Zdzisław Chilmonczyk

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.01 MB

english, 2012

32

Identification of Novel Serotonin Transporter Compounds by Virtual Screening

Gabrielsen, Mari, Kurczab, Rafał, Siwek, Agata, Wolak, Małgorzata, Ravna, Aina W., Kristiansen, Kurt, Kufareva, Irina, Abagyan, Ruben, Nowak, Gabriel, Chilmonczyk, Zdzisław, Sylte, Ingebrigt, Bojarski

Journal:

Journal of Chemical Information and Modeling

Year:

2014

Language:

english

File:

PDF, 1.94 MB

english, 2014

33

Chemokine and chemokine receptor structure and interactions: implications for therapeutic strategies

Kufareva, Irina, Salanga, Catherina L, Handel, Tracy M

Journal:

Immunology & Cell Biology

Year:

2015

Language:

english

File:

PDF, 1.50 MB

english, 2015

34

Orphan receptor ligand discovery by pickpocketing pharmacological neighbors

Ngo, Tony, Ilatovskiy, Andrey V, Stewart, Alastair G, Coleman, James L J, McRobb, Fiona M, Riek, R Peter, Graham, Robert M, Abagyan, Ruben, Kufareva, Irina, Smith, Nicola J

Journal:

Nature Chemical Biology

Year:

2016

Language:

english

File:

PDF, 1.05 MB

english, 2016

35

Structural basis of ligand interaction with atypical chemokine receptor 3

Gustavsson, Martin, Wang, Liwen, van Gils, Noortje, Stephens, Bryan S., Zhang, Penglie, Schall, Thomas J., Yang, Sichun, Abagyan, Ruben, Chance, Mark R., Kufareva, Irina, Handel, Tracy M.

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 2.52 MB

english, 2017

36

Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV

Zheng, Yi, Han, Gye Won, Abagyan, Ruben, Wu, Beili, Stevens, Raymond C., Cherezov, Vadim, Kufareva, Irina, Handel, Tracy M.

Journal:

Year:

2017

Language:

english

File:

PDF, 5.50 MB

english, 2017

37

Lapatinib-Binding Protein Kinases in the African Trypanosome: Identification of Cellular Targets for Kinase-Directed Chemical Scaffolds

Katiyar, Samiksha, Kufareva, Irina, Behera, Ranjan, Thomas, Sarah M., Ogata, Yuko, Pollastri, Michael, Abagyan, Ruben, Mensa-Wilmot, Kojo, Li, Ziyin

Journal:

Year:

2013

Language:

english

File:

PDF, 1.77 MB

english, 2013

38

Investigating Chemokine Receptor CCR2 Dynamics and Druggability by Ensemble Based Approaches

Taylor, Bryn C., Kufareva, Irina, Handel, Tracy, Amaro, Rommie E.

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 40 KB

english, 2018

39

TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin

Swanson, Lee, Katkar, Gajanan D., Tam, Julian, Pranadinata, Rama F., Chareddy, Yogitha, Coates, Jane, Anandachar, Mahitha Shree, Castillo, Vanessa, Olson, Joshua, Nizet, Victor, Kufareva, Irina, Das,

Journal:

Proceedings of the National Academy of Sciences

Year:

2020

File:

PDF, 3.39 MB

2020

40

Type-II Kinase Inhibitor Docking, Screening, and Profiling Using Modified Structures of Active Kinase States

Kufareva, Irina, Abagyan, Ruben

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 3.82 MB

english, 2008

41

A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling

Grimsey, Neil J., Narala, Rachan, Rada, Cara C., Mehta, Sohum, Stephens, Bryan S., Kufareva, Irina, Lapek, John, Gonzalez, David J., Handel, Tracy M., Zhang, Jin, Trejo, JoAnn

Journal:

Year:

2018

Language:

english

File:

PDF, 4.56 MB

english, 2018

42

Tyrosine-based Signals Regulate the assembly of Dapleâ¢PARD3 Complex at Cell-cell Junctions

Ear, Jason, Saklecha, Anokhi, Rajapakse, Navin, Choi, Julie, Ghassemian, Majid, Kufareva, Irina, Ghosh, Pradipta

Journal:

Year:

2020

Language:

english

File:

PDF, 31.19 MB

english, 2020

43

The Angiotensin Receptor Blocker Losartan Suppresses Growth of Pulmonary Metastases via AT1R-Independent Inhibition of CCR2 Signaling and Monocyte Recruitment

Regan, Daniel P., Coy, Jonathan W., Chahal, Kirti Kandhwal, Chow, Lyndah, Kurihara, Jade N., Guth, Amanda M., Kufareva, Irina, Dow, Steven W.

Journal:

The Journal of Immunology

Year:

2019

File:

PDF, 3.12 MB

2019

44

PeptiSite: A structural database of peptide binding sites in 4D

Acharya, Chayan, Kufareva, Irina, Ilatovskiy, Andrey V., Abagyan, Ruben

Journal:

Biochemical and Biophysical Research Communications

Year:

2014

Language:

english

File:

PDF, 2.28 MB

english, 2014

45

Sulfopeptide Probes of the CXCR4/CXCL12 Interface Reveal Oligomer-Specific Contacts and Chemokine Allostery

Ziarek, Joshua J., Getschman, Anthony E., Butler, Stephen J., Taleski, Deni, Stephens, Bryan, Kufareva, Irina, Handel, Tracy M., Payne, Richard J., Volkman, Brian F.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 4.74 MB

english, 2013

46

Chemokines and their receptors: insights from molecular modeling and crystallography

Kufareva, Irina

Journal:

Current Opinion in Pharmacology

Year:

2016

Language:

english

File:

PDF, 3.12 MB

english, 2016

47

Signal transmission through the CXC chemokine receptor 4 (CXCR4) transmembrane helices

Wescott, Melanie P., Kufareva, Irina, Paes, Cheryl, Goodman, Jason R., Thaker, Yana, Puffer, Bridget A., Berdougo, Eli, Rucker, Joseph B., Handel, Tracy M., Doranz, Benjamin J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 1.83 MB

english, 2016

48

Activation of Gαi at the Golgi by GIV/Girdin Imposes Finiteness in Arf1 Signaling

Lo, I-Chung, Gupta, Vijay, Midde, Krishna K., Taupin, Vanessa, Lopez-Sanchez, Inmaculada, Kufareva, Irina, Abagyan, Ruben, Randazzo, Paul A., Farquhar, Marilyn G., Ghosh, Pradipta

Journal:

Developmental Cell

Year:

2015

Language:

english

File:

PDF, 4.69 MB

english, 2015

49

Differential activity and selectivity of Nâterminal modified CXCL12 chemokines at the CXCR4 and ACKR3 receptors

JaraczâRos, Agnieszka, Bernadat, Guillaume, Cutolo, Pasquale, Gallego, Carmen, Gustavsson, Martin, Cecon, Erika, Baleux, FranÃ§oise, Kufareva, Irina, Handel, Tracy M., Bachelerie, FranÃ§oise, Levoye

Journal:

Journal of Leukocyte Biology

Year:

2020

File:

PDF, 2.14 MB

2020

50

In Silico Analysis of the Conservation of Human Toxicity and Endocrine Disruption Targets in Aquatic Species

McRobb, Fiona M., Sahagún, Virginia, Kufareva, Irina, Abagyan, Ruben

Journal:

Environmental Science & Technology

Year:

2014

Language:

english

File:

PDF, 2.23 MB

english, 2014

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